Publications | mysite

2022

Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2.

Sam Afkhami, Michael R D'Agostino, Ali Zhang, Hannah D Stacey, Art Marzok, Alisha Kang, Ramandeep Singh, Jegarubee Bavananthasivam, Gluke Ye, Xiangqian Luo, Fuan Wang, Jann C Ang, Anna Zganiacz, Uma Sankar, Natallia Kazhdan, Joshua F E Koenig, Allyssa Phelps, Steven F Gameiro, Shangguo Tang, Manel Jordana, Yonghong Wan, Karen L Mossman, Mangalakumari Jeyanathan, Amy Gillgrass, Maria Fe C Medina, Fiona Smaill, Brian D Lichty, Matthew S Miller, Zhou Xing. Cell. 20222 March 3. 185 (5): 896-915 e 19. doi: 10.1016/j.cell.2022.02.005. Epub 2022 Feb 9.

Adenovirus 5 Vectors Expressing SARS-CoV-2 Proteins.

Scott Bachus, Nikolas Akkerman, Lauren Fulham, Drayson Graves, Caelan Stephanson, Harram Memon, Matthew S Miller, Peter Pelka. mSphere. 2022 April 27. doi: 10.1128/msphere.00998-21. Epub 2022 Feb 28

Inactivated and live-attenuated seasonal influenza vaccines boost broadly neutralizing antibodies in children.

Sergey Yegorov, Daniel B Celeste, Kimberly Braz Gomes, Jann C Ang, Colin Vandenhof, Joanne Wang, Ksenia Rybkina, Vanessa Tsui, Hannah D Stacey, Mark Loeb, Matthew S Miller.The European respiratory journal. 2022. https://doi.org/10.1183/13993003.02049-2021

A Universal DNA Aptamer that Recognizes Spike Proteins of Diverse SARS-CoV-2 Variants of Concern.

Zijie Zhang, Jiuxing Li, Jimmy Gu, Ryan Amini, Hannah D Stacey, Jann C Ang, Dawn White, Carlos D M Filipe, Karen Mossman, Matthew S Miller, Bruno J Salena, Deborah Yamamura, Payel Sen, Leyla Soleymani, John D Brennan, Yingfu Li. The European respiratory journal. 2022. https://doi.org/10.1183/13993003.02049-2021

Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar-capillary barrier function during influenza infection.

Joshua J C McGrath, Gilles Vanderstocken, Anna Dvorkin-Gheva, Steven P Cass, Sam Afkhami, Matthew F Fantauzzi, Danya Thayaparan, Amir Reihani, Peiyao Wang, Ashley Beaulieu, Pamela Shen, Mathieu Morissette, Rodrigo Jiménez-Saiz, Spencer D Revill, Arata Tabuchi, Diana Zabini, Warren L Lee, Carl D Richards, Matthew S Miller, Kjetil Ask, Wolfgang M Kuebler, Jeremy A Simpson, Martin R Stämpfli. The European respiratory journal. 2022. https://doi.org/10.1183/13993003.02049-2021

Antibody Responses to Third-Dose mRNA Vaccines in Nursing Home and Assisted Living Residents.

Ali Zhang, Jessica A Breznik, Rumi Clare, Ishac Nazy, Matthew S Miller, Dawn M E Bowdish, Andrew P Costa. J Am Med Dir Assoc. 2022 Jan 15;S1525-8610(21)01109-9. doi: 10.1016/j.jamda.2021.12.035

Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice.

Brittany M.Duggan, Akhilesh K.Tamrakar, Nicole G.Barra, Fernando F.Anhê, GabriellaPaniccia, Jessica G.Wallace, Hannah D.Stacey, Michael G.Surette, Matthew S.Miller, Deborah M.Sloboda, Jonathan D.Schertzer. Molecular Metabolism, 2022-01-01, Volume 55, Article 101404

2021

Antibody Responses 3-5 Months Post-Vaccination with mRNA-1273 or BNT163b2 in Nursing Home Residents.

Jessica A Breznik, Ali Zhang, Angela Huynh, Matthew S Miller, Ishac Nazy, Dawn M E Bowdish, Andrew P Costa. J Am Med Dir Assoc. 2021 Dec;22(12):2512-2514. doi: 10.1016/j.jamda.2021.10.001.

Potentiation of long-acting β 2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP.

Yechan Kim, Vincent Hou, Ryan D Huff, Jennifer A Aguiar, Spencer Revill, Nicholas Tiessen, Quynh Cao, Matthew S Miller, Mark D Inman, Kjetil Ask, Andrew C Doxey, Jeremy A Hirota. Respir Res. 2021 Oct 19;22(1):266. doi: 10.1186/s12931-021-01862-1.

High-Affinity Dimeric Aptamers Enable the Rapid Electrochemical Detection of Wild-Type and B.1.1.7 SARS-CoV-2 in Unprocessed Saliva.

Zijie Zhang, Richa Pandey, Jiuxing Li, Jimmy Gu, Dawn White, Hannah D Stacey, Jann C Ang, Catherine-Jean Steinberg, Alfredo Capretta , Carlos D M Filipe, Karen Mossman, Cynthia Balion, Matthew S Miller, Bruno J Salena, Deborah Yamamura, Leyla Soleymani, John D Brennan, Yingfu Li. Angew Chem Int Ed Engl. 2021 Nov 2;60(45):24266-24274. doi: 10.1002/anie.202110819.

Diverse high-affinity DNA aptamers for wild-type and B.1.1.7 SARS-CoV-2 spike proteins from a pre-structured DNA library.

Jiuxing Li, Zijie Zhang, Jimmy Gu, Hannah D Stacey, Jann C Ang, Alfredo Capretta, Carlos D M Filipe, Karen L Mossman, Cynthia Balion, Bruno J Salena, Deborah Yamamura, Leyla Soleymani, Matthew S Miller, John D Brennan, Yingfu Li. Nucleic Acids Res. 2021 Jul 21. doi: 10.1093/nar/gkab574. PMID: 34232998

IgA potentiates NETosis in response to viral infection.

Hannah D Stacey, Diana Golubeva, Alyssa Posca, Jann C Ang, Kyle E Novakowski, Muhammad Atif Zahoor, Charu Kaushic, Ewa Cairns, Dawn M E Bowdish, Caitlin E Mullarkey, Matthew S Miller. Proc Natl Acad Sci U S A. 2021 Jul 6. doi: 10.1073/pnas.2101497118. PMID: 34183391

Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract.

Joshua J C McGrath, Danya Thayaparan, Steven P Cass, Jonathan P Mapletoft, Peter Y F Zeng, Joshua F E Koenig, Matthew F Fantauzzi, Puja Bagri, Bruce Ly, Rachel Heo, L Patrick Schenck, Pamela Shen, Matthew S Miller, Martin R Stämpfli. Mucosal Immunol. 2021 Jun 9. doi: 10.1038/s41385-021-00411-9. Online ahead of print. PMID: 34108594

Neutrophils and Influenza: A Thin Line between Helpful and Harmful.

Sneha T George, Jonathan Lai, Julia Ma, Hannah D Stacey, Matthew S Miller, Caitlin E Mullarkey. Vaccines (BaseI). 2021 Jun 4. doi: 10.3390/vaccines9060597. PMID: 34199803

A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge.

Zachary R Sia, Xuedan He, Ali Zhang, Jann C Ang, Shuai Shao, Amal Seffouh, Wei-Chiao Huang, Michael R D'Agostino, Amir Teimouri Dereshgi, Sambhara Suryaprakash, Joaquin Ortega, Hanne Andersen, Matthew S Miller, Bruce A Davidson, Jonathan F Lovell. Proc Natl Acad Sci U S A. 2021 Jun 1. doi: 10.1073/pnas.2025759118. PMID: 34050027

Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses.

Arinjay Banerjee, Nader El-Sayes, Patrick Budylowski, Rajesh Abraham Jacob, Daniel Richard, Hassaan Maan, Jennifer A Aguiar, Wael L Demian, Kaushal Baid, Michael R D'Agostino, Jann Catherine Ang, Tetyana Murdza, Benjamin J-M Tremblay, Sam Afkhami, Mehran Karimzadeh, Aaron T Irving, Lily Yip, Mario Ostrowski, Jeremy A Hirota, Robert Kozak, Terence D Capellini, Matthew S Miller, Bo Wang, Samira Mubareka, Allison J McGeer, Andrew G McArthur, Andrew C Doxey, Karen Mossman. iScience. 2021 May 21. doi: 10.1016/j.isci.2021.102477. Epub 2021 Apr 26. PMID: 33937724

Covalent Stabilization of Antibody Recruitment Enhances Immune Recognition of Cancer Targets.

Eden Kapcan, Benjamin Lake, Zi Yang, Ali Zhang, Matthew S Miller, Anthony F Rullo. Biochemistry. 2021 May 18. doi: 10.1021/acs.biochem.1c00127. Epub 2021 Apr 30. PMID: 33930269

Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects.

Angela Huynh, Donald M Arnold, James W Smith, Jane C Moore, Ali Zhang, Zain Chagla, Bart J Harvey, Hannah D Stacey, Jann C Ang, Rumi Clare, Nikola Ivetic, Vasudhevan T Chetty, Dawn M E Bowdish, Matthew S Miller, John G Kelton, Ishac Nazy. Viruses. 2021 Apr 16. doi: 10.3390/v13040697. PMID: 33923828

2020

Probe Design for Simultaneous, Targeted Capture of Diverse Metagenomic Targets.

Zachery W Dickson, Dirk Hackenberger, Melanie Kuch, Art Marzok, Arinjay Banerjee, Karen Mossman, Matthew S Miller, Geoffrey B Golding, Hendrik Poinar. Cell Rep Methods. 2020 Dec 23. doi: 10.2139/ssrn.3754546

Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike.

Jérémie Prévost , Romain Gasser , Guillaume Beaudoin-Bussières , Jonathan Richard , Ralf Duerr , Annemarie Laumaea , Sai Priya Anand , Guillaume Goyette , Mehdi Benlarbi , Shilei Ding , Halima Medjahed , Antoine Lewin , Josée Perreault , Tony Tremblay , Gabrielle Gendron-Lepage , Nicolas Gauthier , Marc Carrier , Diane Marcoux , Alain Piché , Myriam Lavoie , Alexandre Benoit , Vilayvong Loungnarath , Gino Brochu , Elie Haddad, Hannah D Stacey , Matthew S Miller , Marc Desforges , Pierre J Talbot , Graham T Gould Maule , Marceline Côté , Christian Therrien , Bouchra Serhir , Renée Bazin , Michel Roger , Andrés Finzi. Cell Rep Med. 2020 Oct 20. 1(7): 100126. DOI: 10.1016/j.xcrm.2020.100126

Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus.

Arinjay Banerjee, Andrew C Doxey, Benjamin J-M Tremblay, Michael J Mansfield, Sonu Subudhi, Jeremy A Hirota, Matthew S Miller, Andrew G McArthur, Samira Mubareka, Karen Mossman. J Gen Virol. 2020 Sep 9. PMID: 32902372. DOI: 10.1099/jgv.0.001491

Immunological considerations for COVID-19 vaccine strategies.

Mangalakumari Jeyanathan, Sam Afkhami, Fiona Smaill, Matthew S Miller, Brian D Lichty, Zhou Xing. Nat. Rev. Immunol. 2020 Sep 4. 1-18. doi: 10.1038/s41577-020-00434-6.

Engineered Nanoparticle Applications for Recombinant Influenza Vaccines.

Zachary R Sia, Matthew S Miller, Jonathan F Lovell. Mol Pharm. 2020 Aug 17. doi: 10.1021/acs.molpharmaceut.0c00383. Online ahead of print.PMID: 32787280

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.

Jennifer A Aguiar, Benjamin J-M Tremblay, Michael J Mansfield, Owen Woody, Briallen Lobb, Arinjay Banerjee, Abiram Chandiramohan, Nicholas Tiessen, Quynh Cao, Anna Dvorkin-Gheva, Spencer Revill , Matthew S Miller, Christopher Carlsten, Louise Organ, Chitra Joseph, Alison John, Paul Hanson , Richard Austin, Bruce M McManus, Gisli Jenkins, Karen Mossman, Kjetil Ask, Andrew C Doxey, Jeremy A Hirota. Eur Respir J. 2020 Jul 16:2001123. doi: 10.1183/13993003.01123-2020. Online ahead of print.PMID: 3267520

Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2.

Arinjay Banerjee, Jalees A Nasir, Patrick Budylowski, Lily Yip, Patryk Aftanas, Natasha Christie, Ayoob Ghalami, Kaushal Baid, Amogelang R Raphenya, Jeremy A Hirota, Matthew S Miller, Allison J McGeer, Mario Ostrowski, Robert A Kozak, Andrew G McArthur, Karen Mossman, Samira Mubareka. Emerg Infect Dis. 2020 Jun 19;26(9). doi: 10.3201/eid2609.201495. Online ahead of print.PMID: 32558639

Bat Influenza Viruses: Making a Double Agent of MHC Class II.

Arinjay Banerjee, Karen L. Mossman, Matthew S. Miller. Trends Microbiol. 2020 Sep;28(9):703-706. doi: 10.1016/j.tim.2020.04.006. Epub 2020 Apr 20.PMID: 3240914

Age-specific incidence of influenza A responds to change in virus subtype dominance.

Alain Gagnon, Erinque Acosta, Matthew S. Miller. Demography. 2019 Oct 28. doi: 10.1007/s13524-019-00824-z. Online ahead of print.PMID: 31659681

Repeated Seasonal Influenza Vaccination-How Much is Too Much of a Good Thing?

Hannah D. Stacey and Matthew S. Miller. J Infect Dis. 2020 Jun 29;222(2):173-175. doi: 10.1093/infdis/jiz434.

2019

Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959-2016.

Acosta, E., Hallman S., Dillon LY, Ouellette N, Bourbeau R, Herring DA, Inwood Kb, Earn DJ, Madrenas J, Miller MS, Gagnon A. Demography. 2019 Oct;56(5):1723-1746.

Comparative Immunogenicity of the 2014–2015 Northern Hemisphere Trivalent IIV and LAIV against Influenza A Viruses in Children.

Jann Catherine Ang, Biao Wang, Joanne J.F. Wang, Peter Yu Fan Zeng, Florian Krammer, Brian J. Ward, Margaret L. Russell, Mark Loeb, and Matthew S. Miller. Vaccines. 2019 August 7. Accepted.

Thermal Stabilization of Viral Vaccines in Low-Cost Sugar Films.

Vincent Leung, Jonathan Mapletoft, Ali Zhang, Amanda Lee, Fatemeh Vahedi, Marianne Chew, Alexandra Szewczyk, Jann Ang, Braeden Cowbrough, Matthew Miller, Ali Ashkar, and Carlos Filipe. Scientific Reports. 2019 May 7. Accepted.

Excipient selection for thermally stable enveloped and non-enveloped viral vaccine platforms in dry powders.

Steve P. Toniolo, Sam Afkhami, Ahmad Mahmood, Cecile Fradin, Brian D. Lichty, Matthew S. Miller, Zhou Xing, Emily D. Cranston, and Michael R. Thompson. International Journal of Pharmaceutics. 2019 February 19;108:173-178. doi: 10.1016/j.ijpharm.2019.02.035.

Original Antigenic Sin: How First Exposure Shapes Lifelong Anti-Influenza Virus Immune Responses.

Ali Zhang, Hannah D. Stacey, Caitlyn E Mullarkey, Matthew S. Miller. J Immunol. 2019 Jan 15;202(2):335-340. doi: 10.4049/jimmunol.1801149.

2018

Reviewing the evidence for viruses as environmental risk factors for ALS: A new perspective.

Daniel B. Celeste and Matthew S. Miller . Cytokine. 2018 Apr 20;108:173-178. doi: 10.1016/j.cyto.2018.04.010.

“Gnothi Seauton”: Leveraging the Host Response to Improve Influenza Virus Vaccine Efficacy

Hannah D. Stacey, Neda Barjesteh, Jonathan P. Mapletoft and Matthew S. Miller . Vaccines 2018, 6(2), 23; doi:10.3390/vaccines6020023

Pandemic Paradox: Early Life H2N2 Pandemic Influenza Infection Enhanced Susceptibility to Death during the 2009 H1N1 Pandemic

Alain Gagnon, Enrique Acosta, Stacey Hallman, Robert Bourbeau, Lisa Y. Dillon, Nadine Ouellette, David J.D. Earn, D. Ann Herring, Kris Inwood, Joaquin Madrenas, Matthew S. Miller. mBio vol 9(1). e2091-17

2017

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice.

Wenqian He*, Chi-Jene Chen, Caitlin E Mullarkey, Jennifer R Hamilton, Christine Wong, Paul E Leon, Melissa B Uccellini, Veronika Chromikova, Carole Henry, Kevin W Hoffman, Jean K Lim, Patrick C Wilson, Matthew S Miller, Florian Krammer, Peter Palese and Gene S Tan. 2017. Nature Communications 8(1):846.

Regulation of kynurenine biosynthesis during influenza virus infection.

Lana Gaelings, Sandra Söderholm, Andrii Bugai, Yu Fu, Jatin Nandania, Bert Schepens, Martina B. Lorey, Janne Tynell, Liesbeth Vande Ginste, Ronan Le Goffic, Matthew S Miller, Marika Kuisma, Varpu Marjomäki, Jef De Brabander, Sampsa Matikainen, Tuula A. Nyman, Dennis H Bamford, Xavier Saelens, Ilkka Julkunen, Henrik Paavilainen, Veijo Hukkanen, Vidya Velagapudi, Dennis E Kainov. 2017. FEBS J. 286:222-236.

2016

Broadly neutralizing hemagglutinin stalk-specific antibodies induce potent phagocytosis of immune complexes by neutrophils in an Fc-dependent manner.

Caitlin E Mullarkey, Mark Bailey, Diana Golubeva, Gene Tan, Raffael Nachbagauer, Wenqian He, Kyle Novakowski, Dawn Bowdish, Matthew S Miller, and Peter Palese. 2016. mBio,7(5), pii: e01624-16.

Abnormal Regulation of the Antiviral Response in Neurological/Neurodegenerative Diseases.

Mannie Man Wai Lam, Jonathan P Mapletoft and Matthew S Miller. 2016. Cytokine, 88:251-258.

Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity (ADCC) against influenza A virus

Wenqian He, Gene S Tan, Caitlin E Mullarkey, Amanda J Lee, Mannie Man Wai Lam, Florian Krammer, Carole Henry, Patrick C Wilson, Ali A Ashkar, Peter Palese and Matthew S Miller. 2016. Proc Natl Acad Sci USA, 113(42):11931-11936.

Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact

Paul E Leon, Wenqian He, Caitlin E Mullarkey, Mark J Bailey, Matthew S Miller, Florian Krammer, Peter Palese and Gene S Tan. 2016. Proc Natl Acad Sci USA, 113(40).

Autoimmune variant PTPN22 C1858T is associated with impaired responses to influenza virus vaccination

Juliet N. Crabtree, Wenqian He, Weihua Guan, Mark Flage, Matthew S Miller, Erik J. Peterson. 2016. J Infect Dis. 214(2): 248-57

CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection

Changying Jiang, Zhicheng Zhou, Yanping Quan, Shilei Zhang, Tingting Wang, Xueqiang Zhao, Clayton Morrison, Mark T. Heise, Wenqian He, Matthew S. Miller, Xin Lin. 2016.Cell Reports. 14(10): 2389-401.

2015

Hemagglutinin stalk immunity reduces influenza virus replication and transmission in ferrets.

Raffael Nachbagauer, Matthew S Miller, Rong Hai, Alex Ryder, John Rose, Peter Palese, Adolfo García-Sastre, Florian Krammer, and Randy Albrecht. 2015. Journal of Virology. 90:3268-73

Measuring the neutralization potency of influenza A virus hemagglutinin stalk/stem-binding antibodies in polyclonal preparations by microneutralization assay.

Wenqian He, Caitlin E Mullarkey and Matthew S. Miller. 2015. Methods pii: S1046-2023(15)00191-7.

SETX suppresses the antiviral transcriptional response and controls viral biogenesis.

Matthew S. Miller, Alexander Rialdi, Jessica Sook Yuin Ho, Micah Tilove, Luis Martinez-Gil, Natasha P. Moshkina, Zuleyma Peralta, Justine Noel, Camilla Melegari, Ana Maestre, Panagiotis Mitsopoulos, Joaquín Madrenas, Sven Heinz, Chris Benner, John A. T. Young, Alicia R. Feagins, Christopher Basler, Ana Fernandez-Sesma, Olivier J. Becherel, Martin F. Lavin, Harm van Bakel, and Ivan Marazzi. 2015. Nat Immunol. 16:485-494.

Is Antigenic Sin always "original?": Re-examining the evidence regarding circulation of a human H1 influenza virus immediately prior to the 1918 Spanish Flu.

Alain Gagnon, Enrique Acosta and Matthew S. Miller. 2015. PLoS Pathog. 11:e1004615

Broadly-Neutralizing Anti-Influenza Virus Antibodies: Enhancement of Neutralizing Potency in Polyclonal Mixtures and IgA Backbones.

Wenqian He, Caitlin Mullarkey, J Duty, Thomas Moran, Peter Palese and Matthew S. Miller. 2015. J Virol 89:3610-3618

2014

Induction of broadly cross reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.Ali H. Ellebedy, Florian Krammer, Gui-Mei Li, Matthew S. Miller, Christopher Chiu, Jens Wrammert, Cathy Y. Cheng, Carl W. Davis, Megan McCausland, Rivka Elbein, Srilatha Edupuganti, Paul Spearman, Sarah F. Andrews, Patrick C. Wilson, Adolfo Garcia-Sastre, Mark J. Mulligan, Aneesh K. Mehta, Peter Palese and Rafi Ahmed. 2014. Proc Natl Acad Sci U S A. 111:13133-13138

Peering into the crystal ball: Predicting influenza pandemics and vaccine efficacy.

Matthew S. Miller and Peter Palese. 2014. Cell 157:294-299

Assessment of influenza virus hemagglutinin stalk-based immunity in ferrets.

Florian Krammer, Rong Hai, Mark Yondola, Gene Tan, Victor Levya-Grado, Alex Ryder, Matthew S. Miller, John Rose, Peter Palese, Adolfo Garcia-Sastre and Randy Albrecht. 2014. J Virol. 88:3432-3442

2013

Neutralizing antibodies against previously-encountered influenza virus strains increase over time: A longitudinal analysis.

Matthew S. Miller, Thomas J. Gardner, Florian Krammer, Lauren C. Aguado, Domenico Tortorella, Christopher F. Basler and Peter Palese. 2013. Sci Transl Med 5:198ra107

Age-specific mortality during the 1918 influenza pandemic: Unravelling the mystery of high young adult mortality.

Alain Gagnon, Matthew S. Miller, Stacey Hallman, Robert Bourbeau, D. Ann Herring, David J.D. Earn and Joaquin Madrenas. 2013. PLoS One 8:e69586.

Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus.

Judith Alamares-Sapuay, Luis Martinez-Gil, Silke Stertz, Matthew S. Miller, Megan Shaw and Peter Palese. 2013. J Virol. 87:6020-6026.

1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans.

Matthew S. Miller, Tshidi Tsibane, Florian Krammer, Rong Hai, Saad Rahmat, Christopher F. Basler and Peter Palese. 2013. J Infect. Dis. 207:98-105.

2012

Characterization of the 55 residue protein encoded by the 9S E1A mRNA of species C adenovirus.

Matthew S. Miller, Peter Pelka, Gregory J. Fonseca, Michael J. Cohen, Jenna N. Kelly, Stephen D. Barr, Roger J. A. Grand, Andrew S. Turnell, Peter Whyte, Joe S. Mymryk. 2012. J Virol. 86:4222-4233

2011

An Unhealthy Relationship: Viral Manipulation of the Nuclear Receptor Superfamily.

Matthew S. Miller and Joe S. Mymryk. 2011. Future Microbiol. 6:999-1019.

Adenovirus E1A directly targets the DP-1/E2F complex.

Peter Pelka, Matthew S. Miller, Matthew Checchini, Ahmed Fayed Yousef, Dawn M. Bowdish, Fred Dick, Peter Whyte and Joe S. Mymryk. 2011. J Virol. 85:8841-8851.

2010

RASCAL is a new human cytomegalovirus-encoded protein localizing to the nuclear lamina and in cytoplasmic vesicles at late times post-infection.

Matthew S. Miller, Leesa Pennell, Wendy E. Furlong, Marc Geadah and Laura Hertel. 2010. J Virol. 84:6483-6496.

2009

Onset of human cytomegalovirus replication in fibroblasts requires the presence of an intact vimentin cytoskeleton.

Matthew S. Miller and Laura Hertel. 2009. J Virol. 83:7015-1728.

Human cytomegalovirus US9 protein contains an N-terminal signal sequence and a C-terminal mitochondrial localization domain, and does not alter cellular sensitivity to apoptosis.

Lana Mandic, Matthew S. Miller, Corinne Coulter, Brian Munshaw and Laura Hertel. 2009. J Gen. Virol. 90:1172-1182

Miller Laboratory